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产品概况
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BE-Gradient: is our device designed for the application of electrochemical gradients to 3D cell cultures. BE-Gradient is compatiblewith any type of optical microscopy (inverted phase contrast, confocal, fluorescence..). Be-Gradient consists of a central chamber for cell culture and two lateral channels connecting to the central chamber through 3 small microchannels. Lateral channels are meant to simulate blood vessels. 2D culture is also possible for adherent cells not only in the central chamber but also in the lateral channels.
Culture Models
• Apply an electrochemical gradient to your 3D cell culture. First mix your cells in a liquid hydrogel and seed them into the central chamber. After hydrogel polymerization has been completed, perfuse culture media with different concentrations of a chemical compound through the lateral channels and monitor the effect in real time.
Device features
• Easy to use: Be-Gradient is compatible with any type of optical microscopy (confocal, fluorescence…) and its slide format has been chosen for easy handling under a microscope.
• Easy to implement: Be-Gradient chambers are positioned in standard positions of a 96 well plate for its use in automated microscopes.
• Easy to connect: Be-Gradient is compatible with all microfluidic flow control systems (syringe, peristaltic pumps, pressure control systems, rocker systems…).
• No unspecific absorption: Unlike in other PDMS devices, Be-Gradientis made of lipophobic thermoplastic materials and does not present unspecific drug absorption issues. Therefore, it allows immunohistochemistry with fluorescent detection.
• Cell recovery option: The cell cultures used in the Be–Gradient can be easily recover for further experimentation
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BE-Gradient: is our device designed for the application of electrochemical gradients to 3D cell cultures. BE-Gradient is compatiblewith any type of optical microscopy (inverted phase contrast, confocal, fluorescence..). Be-Gradient consists of a central chamber for cell culture and two lateral channels connecting to the central chamber through 3 small microchannels. Lateral channels are meant to simulate blood vessels. 2D culture is also possible for adherent cells not only in the central chamber but also in the lateral channels.
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产品特性
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类别Microfluidic Chips
*本产品仅限于专业人员的科学研究使用，不得用于食品、临床诊断或治疗。
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产品应用
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应用说明The BE-Gradient is a chip designed with a very specific function in mind, studying a culture under an electrochemical gradient. This device allows experiments that can never be done in a petri dish such as the application of nutrient, oxygen or drug gradient, the study of cell migration under these conditions, angiogenesis studies and much more.
Chemotactic migration studies
Necrotic core generation within the microdevice
Glucose gradient
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关联文献
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产品概况
